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郝长春
职称/职务: 教授
电话:
传真:
电子信箱: haochangchun@snnu.edu.cn
出生年月:
办公地点: 致知楼3225

教育经历

2007年—2011  陕西师范大学- National Research Council CanadaSteacie Institute for Molecular

                Sciences  联合培养博士

讲授课程

《力学》、《大学物理》、《生物物理学》、《生物物理实验技术和方法》、 《膜与细胞生物物理》

研究方向

1. 生物物理化学

2. 生物医学超声

主持和参与国家自然科学基金、陕西省自然科学基金、陕西师范大学中央高校基金等相关科研项目10余项,撰写和参与发表科研论文80余篇;申请和参与教学改革项目4项, 参与和发表教改论文5篇, 专利若干, 指导本科生申请多项国家级,校级重点大学生创新项目和勤助科研项目;指导的研究生获得国家奖学金,指导本科生参与发表科研论文若干。

第七届免费师范生教育教学能力大赛“优秀指导教师奖”

第九届青年教师教学基本功大赛  二等奖

部分科研项目

1. 主 持 超声作用细胞膜结构的物理机制及生物效应研究2019.01-2022.12 11874039 国家自然科学

   基金面上项目

2. 主 持 超声波作用生物膜结构的物理机制研究2018.01-2019.12 GK201803021 中央高校基本科研

   业务费项目

3. 主 持 不对称双层膜自组装结构构建和理化性质研究2016.01-2017.12 2016JM2010 陕西省自然科学

   基础研究计划面上项目

4. 参 与 超声提取中混沌态复杂流体的空化过程及动力学行为研究 2016.1.1-2016.12.30  11544009 国家

   自然科学基金应急管理项目

5. 主 持 不对称脂膜结构中分子运动规律及膜的稳定性研究 2015.01-2017.12 21402114 国家自然科学

   基金青年科学基金项目

6. 主 持 气液界面脂与牛血清蛋白相互作用研究 2014.7.1-2016.6.20 中国科学院上海应用物理所微观

   界面物理与探测重点实验室开放课题

部分授权专利 

郝长春, 徐广宽, 栾龙, 孙润广. 一种表面活性剂协同双水相提取印楝素的方法 授权公告号: CN106749340B, 专利号:ZL2016 1 1062098.9 授权日:2018-11-02

郝长春 ,逯晓龙, 孙润广. 单分子膜制备仪 授权公告号: CN106480453B, 专利号:ZL2016 1 0919319.3 授权日: 2018-12-07

 

部分论文

1. Haiyan Yang, Changchun Hao*, Hengyu Liu, Kunfeng Zhong, Runguang Sun*. Influence of bovine hemoglobin on the disruption of fluorescence resonance energy transfer between zinc sulfide quantum dots and fluorescent silica nanoparticles. Journal of Molecular Liquids, 2021, https://doi.org/10.1016/j.molliq.2021.115851. 

2. Hengyu Liu, Changchun Hao*, Yanyan Zhang, Haiyan Yang, Runguang Sun*. The Interaction of Graphene Oxide-Silver Nanoparticles with Trypsin: Insights from Adsorption Behaviors, Conformational Structure and Enzymatic Activity Investigations. Colloids and Surfaces B: Biointerfaces, 2021, https://doi.org/10.1016/j.colsurfb.2021.111688

3. Kunfeng Zhong, Changchun Hao*, Hengyu Liu, Haiyan Yang, Runguang Sun*. Synthesis of dual-emissive ratiometric probe of BSA-Au NCs and BSA-Cu NCs and their sensitive and selective detection of copper and mercury ions. Journal of Photochemistry & Photobiology, A: Chemistry, 2021, 408(113110): 1-8

4. Bin Xie*, Changchun Hao*, Runguang Sun. Effect of fluoxetine at different concentrations on the adsorption behavior of Langmuir monolayers, Biochimica et Biophysica Acta (BBA) - Biomembranes, 2020, 1862(183418):1-7.

5. Haiyan Yang, Changchun Hao*, Zhezhu Nan, Runguang Sun*. Bovine hemoglobin adsorption onto modified silica nanoparticles: Multi-spectroscopic measurements based on kinetics and protein conformation, International Journal of Biological Macromolecules, 2020, 155: 208-215.

6. Hongjin Qu, Changchun Hao*, Zhezhu Nan, Xianggang Zhang, Runguang Sun. Modulation of membrane properties by DNA in liposomes: A spectroscopic study. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 224: (117459)1-6.

7. Xianggang Zhang, Changchun Hao*, Chen Ma, Zhuangzhi Shen, Jianzhong Guo, Runguang Sun. Studied on sonocatalytic degradation of Rhodamine B in aqueous solution, Ultrasonics Sonochemistry, 2019, 58: (104691)1-10.

8. Hongjin Qu, Changchun Hao*, Ziyi Zhang, Zhuangwei Xu, Runguang Sun. Adsorption behavior of DNA on phosphatidylcholine at the air-water interface.  Materials Science & Engineering C, 2019,99: 505-510.

9. Zhezhu Nan, Changchun Hao*, Xiaoqi Ye, Ying Feng, Runguang Sun. Interaction of graphene Oxide with bovine serum albumin: A fluoescence quenching study.  Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019,210: 348-354.  

10. Shoujian Song, Changchun Hao*, Xianggang Zhang, Qing Zhang, Runguang Sun. Sonocatalytic degradation of methyl orange in aqueous solution using Fe-doped TiO2 nanoparticles under mechanical agitation. Open Chemistry, 2018, 16: 1283-1296.

11. Xiaoqi Ye, Changchun Hao*, Juanjuan Yang, Runguang Sun. Influence of modified silica nanoparticles on phase behavior and structure properties of DPPC monolayers. Colloids and Surfaces B: Biointerfaces, 2018, 172: 480-486.  

12. Juanjuan yang, Changchun Hao*, Runguang Sun. Effect of Laminaria japonica polysaccharides on lipids monolayers at the air-water surface. Colloids and Surfaces B: Biointerfaces, 2018, 161: 614-619.

13. Changchun Hao*, Juanjuan Yang, Tao Liang, Jing Zhang, Runguang Sun. Structural elucidation and morphological observation of a polysaccharide from Pleurotus eryngii obtained by alkaline extraction. Journal of Carbohydrate Chemistry, 2017, 36(2-3): 129-140.

14. Changchun Hao*, Guangkuan Xu, Ying Feng, Linhao Lu, Wenyuan Sun, Runguang Sun. Fluorescence quenching study on the interaction of ferroferric oxide nanoparticles with bovine serum albumin. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2017, 184: 191-197.

15. Suyang Tian, Changchun Hao*, Guangkuan Xu, Juanjuan Yang, Runguang Sun. Optimization conditions for extracting polysaccharide from Angelica sinensis and its antioxidant activities. Journal of Food and Drug Analysis, 2017, 25: 766-775.

16. Shi Chen, Wenxu Hu, Chenghui Wang, Changchun Hao, Zhen Xu, Yinhong Zhang, Shuyu Lin. Enhancement of backward second harmonic generation of acoustic waves in a resonant cavity by using a superlattice. Ultrasonics, 2017, 73:107-113.

17. Lei Zhang, Changchun Hao*, Shengju Wu, Xiaolong Lu, Junhua Li, Runguang Sun, A thermodynamic analysis of the effects of Myelin Basic Protein (MBP) on DPPS and DPPG monolayers, Colloids Surf A Physicochemical and Engineering Aspects, 2016, 511:303-311.

18. Changchun Hao*, Junhua Li, Wenning Mu, Lingqing Zhu, Jiaxiang Yang, Hongwei Liu, Bin Li, Shi Chen, Runguang Sun, Adsorption behavior of magnetite nanoparticles into the DPPC model membranes, Applied Surface Science, 2016, 362, 121-125.

19.  Junhua Li, Runguang Sun, Changchun Hao*, Guangxiao He, Lei Zhang, Juan Wang. The behavior of the adsorption of cytochrome C on lipid monolayers: a study by the Langmuir-Blodgett technique and theoretical analysis, Biophysical Chemistry, 2015, 205: 33-40.

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