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郝长春
职称/职务: 副教授
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电子信箱: haochangchun@snnu.edu.cn
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办公地点: 致知楼3225

教育经历

2007年—2011  陕西师范大学- National Research Council CanadaSteacie Institute 

                          for Molecular Sciences  联合培养博士

讲授课程

《力学》、《大学物理》、《生物物理学》、《生物物理实验技术和方法》、

《膜与细胞生物物理》

研究方向

1. 生物物理化学

2. 生物医学超声

主持和参与国家自然科学基金、陕西省自然科学基金、陕西师范大学中央高校基金等相关科研项目10余项,撰写和参与发表科研论文80余篇;申请和参与教学改革项目4项, 参与和发表教改论文5篇, 专利若干, 指导本科生申请多项国家级,校级重点大学生创新项目和勤助科研项目;指导的研究生获得国家奖学金,指导本科生参与发表科研论文若干。

第七届免费师范生教育教学能力大赛“优秀指导教师奖”

第九届青年教师教学基本功大赛  二等奖

 

部分科研项目

1.        主持 超声作用细胞膜结构的物理机制及生物效应研究2019.01-2022.12 11874039 国家自然科学基金面上项目

              主持 超声波作用生物膜结构的物理机制研究2018.01-2019.12 GK201803021 中央高校基本科研业务费项目

             主持 不对称双层膜自组装结构构建和理化性质研究2016.01-2017.12 2016JM2010 陕西省自然科学基础研究计划面上项目

3.        参与 超声提取中混沌态复杂流体的空化过程及动力学行为研究 2016.1.1-2016.12.30  11544009 国家自然科学基金应急管理项目

5.        主持 不对称脂膜结构中分子运动规律及膜的稳定性研究 2015.01-2017.12 21402114 国家自然科学基金青年科学基金项目

6.        主持 气液界面脂与牛血清蛋白相互作用研究 2014.7.1-2016.6.20 中国科学院上海应用物理所微观界面物理与探测重点实验室开放课题

 

部分科研论文

     Shoujian Song, Changchun Hao, Xianggang Zhang, Qing Zhang, Runguang Sun. Sonocatalytic degradation of methyl orange in aqueous solution using Fe-doped TiO2 nanoparticles under mechanical agitation. Open Chemistry, 2018, Accepted.(通讯作者)         

       Xiaoqi Ye, Changchun Hao, Juanjuan Yang, Runguang Sun. Influence of modified silica nanoparticles on phase behavior and structure properties of DPPC monolayers. Colloids and Surfaces B: Biointerfaces, 2018, 172: 480-486.  (通讯作者,SCI二区)

           Juanjuan yang, Changchun Hao, Runguang Sun. Effect of Laminaria japonica polysaccharides on lipids monolayers at the air-water surface. Colloids and Surfaces B: Biointerfaces, 2018, 161: 614-619.  (通讯作者,SCI二区)

2.        Guoqing Xu, Changchun Hao, Lei Zhang, Runguang Sun, Investigation of surface behavior of DPPC and Curcumin in Langmuir monolayers at the air/water interface, Scanning, 2017, (2017): Article ID: 6582019, 1-12. (通讯作者)

3.        Guoqing Xu, Changchun Hao, Lei Zhang, Shi Chen, Runguang Sun. Dynamic behaviors and morphology change of anionic phospholipid DPPG monolayer caused by BSA at air-water interface, Chinese Journal of Chemical Physics, 2017, 30595-602.(通讯作者)

4.        徐国庆, 郝长春, 赫剑真, 张蕾, 孙润广. 牛血清蛋白对DSPE单层膜结构影响的研究, 高等学校化学学报, 2017, 38(12): 2238-2247.(封面,通讯作者)

5.        Changchun Hao, Juanjuan Yang, Tao Liang, Jing Zhang, Runguang Sun. Structural elucidation and morphological observation of a polysaccharide from Pleurotus eryngii obtained by alkaline extraction. Journal of Carbohydrate Chemistry, 2017, 36(2-3): 129-140.

6.        Changchun Hao, Guangkuan Xu, Ying Feng, Linhao Lu, Wenyuan Sun, Runguang Sun. Fluorescence quenching study on the interaction of ferroferric oxide nanoparticles with bovine serum albumin. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2017, 184: 191-197. (SCI二区)

7.        Suyang Tian, Changchun Hao, Guangkuan Xu, Juanjuan Yang, Runguang Sun. Optimization conditions for extracting polysaccharide from Angelica sinensis and its antioxidant activities. Journal of Food and Drug Analysis, 2017, 25: 766-775.(通讯作者)

8.        Guangkuan Xu, Changchun Hao, Suyang Tian, Feng Gao, Wenyuan Sun, Runguang Sun, A method for the preparation of curcumin by ultrasonic-assisted ammonium sulfate/ethanol aqueous two phase extraction, Journal of Chromatography B, 2017, 1041: 167-174.(通讯作者)

9.        Shi Chen, Wenxu Hu, Chenghui Wang, Changchun Hao, Zhen Xu, Yinhong Zhang, Shuyu Lin. Enhancement of backward second harmonic generation of acoustic waves in a resonant cavity by using a superlattice. Ultrasonics, 2017, 73:107-113.

10.    Lei Zhang, Changchun Hao, Shengju Wu, Xiaolong Lu, Junhua Li, Runguang Sun, A thermodynamic analysis of the effects of Myelin Basic Protein (MBP) on DPPS and DPPG monolayers, Colloids Surf A Physicochemical and Engineering Aspects, 2016, 511:303-311.(通讯作者)

11.    Huaze Zhu, Runguang Sun, Changchun Hao, Pengli Zhang. A Langmuir and AFM study on interfacial behavior of binary monolayer of hexadecanol/DPPE at the air-water interface, Chemistry and Physics of Lipids, 2016, 201: 11-20.

12.    赵志杰, 张萍, 杨家香, 郝长春, 周星飞, 李宾. 液体环境单分子免疫球蛋白G的原子力显微镜高分辨成像. 分析化学, 2016, 44(8):1215-1220.

13.    Zhang Lei, Hao Changchun, Feng Ying, Lu Xiaolong, Li Junhua, Sun Runguang. Analysis of the induction of the Myelin Basics Protein binding to the plasma membrane phospholipid monolayer. Chinese Physics B, 2016, 25(9): 090507-1--7.(通讯作者)

14.    Changchun Hao, Junhua Li, Wenning Mu, Lingqing Zhu, Jiaxiang Yang, Hongwei Liu, Bin Li, Shi Chen, Runguang Sun, Adsorption behavior of magnetite nanoparticles into the DPPC model membranes, Applied Surface Science, 2016, 362, 121-125. (SCI二区)

15.    Junhua Li, Runguang Sun, Changchun Hao, Guangxiao He, Lei Zhang, Juan Wang. The behavior of the adsorption of cytochrome C on lipid monolayers: a study by the Langmuir-Blodgett technique and theoretical analysis, Biophysical Chemistry, 2015, 205: 33-40.(通讯作者)

16.    Shi Chen, Changchun Hao, Chenghui Wang, Yinhong Zhang, Shuyu Lin. One-dimensional acoustic diodes based on the anisotropy of solid media and linear acoustics. Solid State Communications, 2015, 206: 38-41.

17.    Wang Juan, Sun Runguang, Hao Changchun, Mixed alkaline phosphatase/sphingomyelin monolayer at the air-buffer interface: phase behavior and morphology, Science in China Series B: Chemistry, 2014, 57(11): 1538-1543.

18.    张蕾, 孙润广, 郝长春, 杨静, 何光晓. 髓鞘碱性蛋白对细胞膜脂质分子DPPCDPPE单层膜影响机理的研究. 中国科学(B:化学), 2014, 44(10): 1562-1569.(通讯作者)

19.    Changchun Hao, Lei Zhang, Runguang Sun, Jing Zhang, Guangxiao He, Interaction between ganglioside GM1 and diosgenin in Langmuir monolayers at the air/water interface. Scanning, 2014, 36: 218-223.

20.    Hao Changchun, Sun Runguang, Zhang Jing. Mixed monolayers of DOPC and Palmitic acid at the liquid-air interface. Colloids Surf B Biointerfaces, 2013, 112: 441-445.(SCI二区)

21.    Changchun Hao, Runguang Sun, Jing Zhang. Interaction of egg-sphingomyelin with DOPC in Langmuir monolayers. Chinese Journal of Chemical Physics, 2012, 25(6): 691-695.

22.    Ruby May A. Sullan, James K. Li, Changchun Hao, Gilbert C. Walker, Shan Zou. Cholesterol-dependent nanomechanical stability of phase-segregated multicomponent lipid bilayers . Biophys J, 2010, 99: 507-516.(SCI二区)

23.    Hao Changchun, Sun Runguang, Zhang Jing, Chang Yiguang, Niu Chunling. Thermodynamic behavior of D-sphingosine/cholesterol monolayers and the topography observed by AFM . Science in China Series B: Chemistry, 2009, 52: 219-225.

24.    Hao Changchun, Sun Runguang, Zhang Jing, Chang Yiguang, Niu Chunling. Behavior of sulfatide/cholesterol mixed monolayers at the air/water interface . Colloids Surf B Biointerfaces, 2009, 69: 201-206.(SCI二区)

 

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